DegronMD - Q96MK2(RIPOR3)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P347L	SIDM01953	Colorectal Carcinoma	GDSC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation rewiring degron network	0.1389
p.P347S	SIDM00267	Biliary Tract Carcinoma	GDSC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation rewiring degron network	0.1389
p.P347S	SIDM00302	Other Solid Cancers	GDSC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation rewiring degron network	0.1389
p.P347S	TGBC24TKB	biliary tract	COSMIC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation rewiring degron network	0.1389
p.P347S	KGN	ovary	COSMIC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation rewiring degron network	0.1389
p.Y356C	SIDM01659	Kidney Carcinoma	GDSC	ERYYLSVLQ	DEG_APCC_DBOX_1	354:362	Mutation altering degron motif	0.5976

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons