DegronMD - Q96N95(ZNF396)

ZNF396

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S198Y	TCGA-5C-AAPD	LIHC	TCGA	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation rewiring degron network	0.0833
p.S198Y	DO52168	LIHC	ICGC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation rewiring degron network	0.0833
p.D190V	TCGA-AX-A1CE	UCEC	TCGA	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation rewiring degron network	0.3056
p.D190V	DO42280	UCEC	ICGC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation rewiring degron network	0.3056
p.S183Y	DO229031	LICA	ICGC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation rewiring degron network	0.3056
p.P186L	SIDM00716	Squamous Cell Lung Carcinoma	GDSC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation altering degron motif	0.6471
p.P186L	ACH-000481	Lung Cancer	CCLE	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation altering degron motif	0.6471
p.P186L	NCI-H2170	lung	COSMIC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation altering degron motif	0.6471
p.P186S	SIDM00412	B-Cell Non-Hodgkin's Lymphoma	GDSC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation altering degron motif	0.6752
p.P186S	WSU-NHL	haematopoietic and lymphoid tissue	COSMIC	LRPHDE	LIG_APCC_ABBA_1	184:189	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc