DegronMD - Q96PJ5(FCRL4)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L189Q	TCGA-14-1451	GBM	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.7765
p.L189Q	DO13384	GBM	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.7765
p.P193S	TCGA-AX-A06F	UCEC	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.5641
p.P193S	DO41752	UCEC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.5641
p.L189I	TCGA-B5-A11E	UCEC	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6063
p.L189I	DO41644	UCEC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6063
p.E194D	TCGA-CV-7254	HNSC	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.5647
p.E194D	DO14168	HNSC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.5647
p.K185R	TCGA-CZ-4865	KIRC	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation substituting flanking lysine	0.3333
p.K185R	DO16741	KIRC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation substituting flanking lysine	0.3333
p.P191S	TCGA-D8-A1JG	BRCA	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6752
p.P191S	DO1256	BRCA	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6752
p.E194Q	TCGA-DI-A1NO	UCEC	TCGA	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6744
p.E194Q	DO41662	UCEC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.6744
p.E204D	DO234348	ESAD	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.0556
p.K196N	DO234378	ESAD	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.2778
p.P193Q	DO229037	LICA	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation altering degron motif	0.5924
p.S200C	DO230968	LUSC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.1667
p.S200C	DO224621	LUSC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.1667
p.T198I	DO231165	LUSC	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.2222
p.I186T	DO229216	THCA	ICGC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.25
p.I184L	SIDM01611	Endometrial Carcinoma	GDSC	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.1944
p.I184L	ACH-000996	Endometrial/Uterine Cancer	CCLE	LFPHPE	LIG_APCC_ABBA_1	189:194	Mutation rewiring degron network	0.1944

Kaplan plot for FCRL4 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FCRL4

UniProt ID: Q96PJ5

Entrez ID: 83417

Protein name: Fc receptor-like protein 4 (FcR-like protein 4) (FcRL4) (Fc receptor homolog 4) (FcRH4) (IFGP family protein 2) (hIFGP2) (Immune receptor translocation-associated protein 1) (CD antigen CD307d)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FCRL4 in