DegronMD - Q96PQ1(SIGLEC12)

SIGLEC12

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A552T	TCGA-59-A5PD	OV	TCGA	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.3056
p.Q564H	TCGA-66-2763	LUSC	TCGA	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1944
p.Q564K	TCGA-99-AA5R	LUAD	TCGA	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1944
p.E560K	TCGA-EE-A2GC	SKCM	TCGA	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.3056
p.H548Q	SIDM00186	Kidney Carcinoma	GDSC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1944
p.H548Q	SIDM01651	Non-Cancerous	GDSC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1944
p.H548Q	ACH-002353	Non-Cancerous	CCLE	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1944
p.P545H	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111
p.P545H	ACH-000929	Lung Cancer	CCLE	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111
p.P545H	NCI-H2110	lung	COSMIC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111
p.P545T	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111
p.P545T	ACH-000929	Lung Cancer	CCLE	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111
p.P545T	NCI-H2110	lung	COSMIC	LATPSPE	DEG_SCF_FBW7_2	553:559	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc