DegronMD - Q96QE5(TEFM)

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GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R34W	TCGA-BS-A0UV	UCEC	TCGA	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.0833
p.R34W	DO42793	UCEC	ICGC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.0833
p.R34W	SIDM01510	Non-Small Cell Lung Carcinoma	GDSC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.0833
p.D51A	TCGA-D7-A4Z0	STAD	TCGA	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.25
p.D51A	DO47765	STAD	ICGC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.25
p.P45H	SIDM00217	Colorectal Carcinoma	GDSC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation altering degron motif	0.7694
p.P45H	ACH-000999	Colon/Colorectal Cancer	CCLE	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation altering degron motif	0.7694
p.P45H	SNU-1040	large intestine	COSMIC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation altering degron motif	0.7694
p.C50F	SIDM01611	Endometrial Carcinoma	GDSC	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.2778
p.C50F	ACH-000996	Endometrial/Uterine Cancer	CCLE	ITPNVT	DEG_SCF_FBW7_1	43:48	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons