DegronMD - Q96RD6(PANX2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D392A	DO230312	COCA	ICGC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1389
p.A412T	DO222853	COCA	ICGC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1111
p.V405L	DO228766	LICA	ICGC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.3056
p.P411L	DO229177	LMS	ICGC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1389
p.D392N	DO220906	MELA	ICGC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1389
p.T394I	SIDM01119	Other Solid Cancers	GDSC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1944
p.T394I	SIDM00117	Non-Small Cell Lung Carcinoma	GDSC	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1944
p.P414S	ACH-000779	Lung Cancer	CCLE	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.0556
p.N410T	ACH-000880	Gastric Cancer	CCLE	DSGVQT	DEG_SCF_TRCP1_1	399:404	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons