DegronMD - Q96RD9(FCRL5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q669H	TCGA-39-5021	LUSC	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1389
p.Q669H	DO27397	LUSC	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1389
p.L683M	TCGA-85-7697	LUSC	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.2778
p.L683M	DO27053	LUSC	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.2778
p.A670D	TCGA-DU-6392	LGG	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.A670D	DO22237	LGG	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.L690M	TCGA-E6-A1LX	UCEC	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.0833
p.L690M	DO41020	UCEC	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.0833
p.S687F	TCGA-EB-A431	SKCM	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.S687F	DO37671	SKCM	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.R667W	TCGA-FU-A40J	CESC	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.0833
p.R667W	DO44314	CESC	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.0833
p.R667W	ACH-000872	Lung Cancer	CCLE	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.0833
p.P688Q	TCGA-IN-AB1X	STAD	TCGA	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1389
p.P688Q	DO222334	STAD	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1389
p.A682V	DO234275	ESAD	ICGC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.3056
p.V671L	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1944
p.V671L	H513	pleura	COSMIC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1944
p.I689V	SIDM01133	Other Solid Cancers	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1111
p.I689V	SIDM00930	Osteosarcoma	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1111
p.I689V	SIDM00531	Pancreatic Carcinoma	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1111
p.I689V	SIDM01525	Acute Myeloid Leukemia	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1111
p.S687C	SIDM00774	Breast Carcinoma	GDSC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.S687C	ACH-000691	Breast Cancer	CCLE	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667
p.S687C	HCC2157	breast	COSMIC	LELHCE	LIG_APCC_ABBA_1	676:681	Mutation rewiring degron network	0.1667

Kaplan plot for FCRL5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FCRL5

UniProt ID: Q96RD9

Entrez ID: 83416

Protein name: Fc receptor-like protein 5 (FcR-like protein 5) (FcRL5) (BXMAS1) (Fc receptor homolog 5) (FcRH5) (Immune receptor translocation-associated protein 2) (CD antigen CD307e)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FCRL5 in