DegronMD - Q96SY0(INTS14)

INTS14

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R384Q	SIDM01047	Chronic Myelogenous Leukemia	GDSC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation rewiring degron network	0.1944
p.L388V	SIDM00363	Acute Myeloid Leukemia	GDSC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation rewiring degron network	0.0833
p.L388V	SIDM01682	Gastric Carcinoma	GDSC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation rewiring degron network	0.0833
p.L388V	P31-FUJ	haematopoietic and lymphoid tissue	COSMIC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation rewiring degron network	0.0833
p.L366V	P31-FUJ	haematopoietic and lymphoid tissue	COSMIC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation rewiring degron network	0.0833
p.D377V	PEO1	ovary	COSMIC	AKENP	DEG_APCC_KENBOX_2	375:379	Mutation altering degron motif	0.7785

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*NOTE: the Kaplan plots were collected from OncoLnc