DegronMD - Q99675(CGRRF1)

CGRRF1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S260P	TCGA-31-1959	OV	TCGA	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.2778
p.S260P	DO28281	OV	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.2778
p.S260C	TCGA-CG-5717	STAD	TCGA	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.2778
p.S260C	DO38272	STAD	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.2778
p.G258E	TCGA-IB-7651	PAAD	TCGA	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6087
p.G258E	DO46657	PAAD	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6087
p.E245K	TCGA-MV-A51V	BLCA	TCGA	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.1944
p.E245K	DO474	BLCA	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.1944
p.E268K	DO50970	LICA	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.0556
p.S267L	DO232761	PBCA	ICGC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.0833
p.S252G	SIDM00245	Small Cell Lung Carcinoma	GDSC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6993
p.S252G	ACH-001131	Skin Cancer	CCLE	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6993
p.S252G	ACH-001958	lung	CCLE	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6993
p.S252G	MS-1	lung	COSMIC	DRSLLEKVG	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.6993

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*NOTE: the Kaplan plots were collected from OncoLnc