DegronMD - Q99797(MIPEP)

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GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G67E	TCGA-BA-5556	HNSC	TCGA	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.6087
p.G67E	DO14232	HNSC	ICGC	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.6087
p.L65H	TCGA-FI-A2D5	UCEC	TCGA	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.7313
p.L65H	DO41331	UCEC	ICGC	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.7313
p.R62C	SIDM00907	Burkitt's Lymphoma	GDSC	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.8301
p.R62P	SIDM01387	Small Cell Lung Carcinoma	GDSC	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation altering degron motif	0.7512
p.L58M	ACH-001061	Colon/Colorectal Cancer	CCLE	ERRGLFGVP	DEG_APCC_DBOX_1	61:69	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons