DegronMD - Q99805(TM9SF2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S9Y	TCGA-BK-A6W3	UCEC	TCGA	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1944
p.S9Y	DO50076	UCEC	ICGC	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1944
p.R31H	TCGA-TS-A8AI	MESO	TCGA	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.0833
p.S20L	DO50410	ESAD	ICGC	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation altering degron motif	0.7667
p.L17S	DO44664	LICA	ICGC	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation altering degron motif	0.6556
p.V7M	SIDM01609	Endometrial Carcinoma	GDSC	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1389
p.V7M	ACH-000972	Endometrial/Uterine Cancer	CCLE	PRLLLLSLL	DEG_APCC_DBOX_1	14:22	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons