DegronMD - Q9BPX3(NCAPG)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D972N	TCGA-A5-A0G2	UCEC	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation altering degron motif	0.6932
p.D972N	DO41235	UCEC	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation altering degron motif	0.6932
p.D972N	ACH-002048	Sarcoma	CCLE	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation altering degron motif	0.6932
p.R989K	TCGA-AX-A06F	UCEC	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1389
p.R989K	DO41752	UCEC	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1389
p.E970D	TCGA-CA-6717	COAD	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.2778
p.E970D	DO8264	COAD	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.2778
p.T968I	TCGA-CS-6188	LGG	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation blocking phosphorylation signal	0.6667
p.T968I	DO22115	LGG	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation blocking phosphorylation signal	0.6667
p.M988I	TCGA-D5-6535	COAD	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1667
p.M988I	DO10397	COAD	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1667
p.Q967H	TCGA-D5-6930	COAD	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1944
p.Q967H	DO10550	COAD	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1944
p.T962P	TCGA-GS-A9TZ	DLBC	TCGA	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.0556
p.T962P	DO219918	DLBC	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.0556
p.R965M	DO229009	LICA	ICGC	DSESDHEVPEP	DEG_COP1_1	972:982	Mutation rewiring degron network	0.1389

Kaplan plot for NCAPG in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NCAPG

UniProt ID: Q9BPX3

Entrez ID: 64151

Protein name: Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NCAPG in