DegronMD - Q9BQI9(NRIP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E32Q	TCGA-24-2290	OV	TCGA	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.25
p.E32Q	DO30090	OV	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.25
p.E32Q	SIDM00632	Non-Cancerous	GDSC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.25
p.E32Q	ACH-002247	Non-Cancerous	CCLE	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.25
p.E32Q	IM-9	haematopoietic and lymphoid tissue	COSMIC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.25
p.P37L	TCGA-BT-A3PJ	BLCA	TCGA	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation altering degron motif	0.7582
p.P37L	DO44097	BLCA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation altering degron motif	0.7582
p.G28E	TCGA-EE-A3JD	SKCM	TCGA	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1389
p.G28E	DO50299	SKCM	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1389
p.P47T	TCGA-F7-A61V	HNSC	TCGA	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1389
p.P47T	DO44437	HNSC	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1389
p.P44H	DO222794	COCA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.2222
p.Q26K	DO233158	GACA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.0833
p.Q26K	DO229025	LICA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.0833
p.S34P	DO233792	GACA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.3056
p.A48E	DO229063	LICA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1111
p.P47S	DO50970	LICA	ICGC	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation rewiring degron network	0.1389
p.P38S	ACH-002024	Colon/Colorectal Cancer	CCLE	VTPPPS	DEG_SCF_FBW7_1	35:40	Mutation altering degron motif	0.5641

Kaplan plot for NRIP2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NRIP2

UniProt ID: Q9BQI9

Entrez ID: 83714

Protein name: Nuclear receptor-interacting protein 2

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NRIP2 in