DegronMD - Q9BR09(NEURL2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D199E	TCGA-BR-4369	STAD	TCGA	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.D199E	DO38659	STAD	ICGC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.D199N	TCGA-BR-6852	STAD	TCGA	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.D199N	DO38202	STAD	ICGC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.D199Y	TCGA-MU-A8JM	CESC	TCGA	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.D199Y	DO49002	CESC	ICGC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1944
p.G200D	DO233168	GACA	ICGC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.1667
p.P196R	SIDM00447	B-Lymphoblastic Leukemia	GDSC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.2778
p.P196R	ACH-000960	Leukemia	CCLE	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.2778
p.P196R	REH	haematopoietic and lymphoid tissue	COSMIC	RRSRLGVLF	DEG_APCC_DBOX_1	186:194	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons