DegronMD - Q9BRB3(PIGQ)

PIGQ

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L743P	TCGA-AJ-A3EK	UCEC	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.1667
p.L743P	DO41584	UCEC	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.1667
p.P723H	TCGA-AX-A3FS	UCEC	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.0833
p.P723H	DO40879	UCEC	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.0833
p.K729T	TCGA-CC-A8HV	LIHC	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation substituting flanking lysine	0.3611
p.K729T	DO52189	LIHC	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation substituting flanking lysine	0.3611
p.V735I	TCGA-CK-6746	COAD	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.5965
p.V735I	TCGA-IB-7651	PAAD	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.5965
p.V735I	DO7938	COAD	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.5965
p.V735I	DO46657	PAAD	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.5965
p.P734T	TCGA-FS-A1Z0	SKCM	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.7031
p.P734T	DO37431	SKCM	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation altering degron motif	0.7031
p.P739L	TCGA-Z2-AA3S	SKCM	TCGA	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.2778
p.P739L	DO51302	SKCM	ICGC	LTPVPS	DEG_SCF_FBW7_1	732:737	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc