DegronMD - Q9BSD7(NTPCR)

NTPCR

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.C184Y	TCGA-5R-AA1C	LIHC	TCGA	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.0556
p.C184Y	DO219545	LIHC	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.0556
p.V166L	TCGA-94-A5I4	LUSC	TCGA	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.2222
p.V166L	DO219175	LUSC	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.2222
p.D176N	DO52500	EOPC	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.2778
p.Y171C	DO223145	ESCA	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation altering degron motif	0.7087
p.Y171C	DO229047	LICA	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation altering degron motif	0.7087
p.T183R	DO227516	LAML	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.0833
p.P179S	DO45299	LIRI	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.1944
p.V169I	DO229221	THCA	ICGC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation rewiring degron network	0.3056
p.E172K	SIDM01007	T-Lymphoblastic Leukemia	GDSC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation altering degron motif	0.7022
p.E172K	ACH-002256	Leukemia	CCLE	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation altering degron motif	0.7022
p.E172K	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	TKENR	DEG_APCC_KENBOX_2	170:174	Mutation altering degron motif	0.7022

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*NOTE: the Kaplan plots were collected from OncoLnc