DegronMD - Q9BSJ6(PIMREG)

PIMREG

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R179W	SIDM01307	Colorectal Carcinoma	GDSC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.1389
p.A182V	SIDM01612	Endometrial Carcinoma	GDSC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.2222
p.R176Q	SUP-B15	haematopoietic and lymphoid tissue	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.0556
p.R176Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.0556
p.R176Q	DOK	upper aerodigestive tract	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.0556
p.R176Q	HCC-366	lung	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.0556
p.R193C	TE-5	oesophagus	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.25
p.R193C	SiHa	cervix	COSMIC	PYSST	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc