DegronMD - Q9BT09(CNPY3)

CNPY3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E253G	TCGA-17-Z023	LUAD	TCGA	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation altering degron motif	0.6087
p.G238S	TCGA-AC-A2QH	BRCA	TCGA	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.1389
p.G238S	DO2061	BRCA	ICGC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.1389
p.P258L	TCGA-EE-A2MS	SKCM	TCGA	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.1944
p.P258L	DO37567	SKCM	ICGC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.1944
p.D261Y	DO229015	LICA	ICGC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.1111
p.E248K	DO218855	SKCA	ICGC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation altering degron motif	0.591
p.G263D	SIDM00447	B-Lymphoblastic Leukemia	GDSC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.0556
p.G263D	ACH-000960	Leukemia	CCLE	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.0556
p.G263D	REH	haematopoietic and lymphoid tissue	COSMIC	QRKELGGLE	DEG_APCC_DBOX_1	245:253	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc