DegronMD - Q9BT92(TCHP)

TCHP

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K76N	TCGA-K4-A6MB	BLCA	TCGA	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation substituting flanking lysine	0.25
p.K76N	DO44077	BLCA	ICGC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation substituting flanking lysine	0.25
p.E81K	DO229221	THCA	ICGC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2778
p.R78M	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.1944
p.R78M	ACH-000444	Lung Cancer	CCLE	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.1944
p.R78M	LU-99A	lung	COSMIC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.1944
p.E93K	SIDM00934	Pancreatic Carcinoma	GDSC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2778
p.E93K	CAPAN-1	pancreas	COSMIC	RREKLRQLM	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc