DegronMD - Q9BTV6(DPH7)

DPH7

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T364M	TCGA-F5-6814	READ	TCGA	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.0833
p.T364M	DO36556	READ	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.0833
p.P376H	TCGA-FI-A2F4	UCEC	TCGA	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation altering degron motif	0.7694
p.P376H	DO43434	UCEC	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation altering degron motif	0.7694
p.H378Y	DO48366	BLCA	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation altering degron motif	0.6118
p.N384K	DO229028	LICA	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1944
p.L367M	DO229037	LICA	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1667
p.G386R	DO46354	OV	ICGC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1389
p.D366Y	SIDM00789	Colorectal Carcinoma	GDSC	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1389
p.D366Y	ACH-000997	Colon/Colorectal Cancer	CCLE	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1389
p.D366Y	ACH-001061	Colon/Colorectal Cancer	CCLE	LPTPCHE	DEG_SCF_FBW7_2	373:379	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc