DegronMD - Q9BVC4(MLST8)

MLST8

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R54H	TCGA-AU-6004	COAD	TCGA	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7133
p.R54H	DO7780	COAD	ICGC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7133
p.E49D	TCGA-EE-A20F	SKCM	TCGA	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.5647
p.E49D	DO37961	SKCM	ICGC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.5647
p.A60S	DO228948	LICA	ICGC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation rewiring degron network	0.1944
p.V45L	DO229022	LICA	ICGC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation rewiring degron network	0.25
p.P52A	SIDM00980	Gastric Carcinoma	GDSC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7503
p.P52A	ACH-000948	Gastric Cancer	CCLE	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7503
p.P52A	23132-87	stomach	COSMIC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7503
p.P52L	SIDM01322	Oral Cavity Carcinoma	GDSC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7582
p.P52L	ACH-000735	Head and Neck Cancer	CCLE	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7582
p.P51A	23132-87	stomach	COSMIC	LEVTPDRS	DEG_SCF_FBW7_1	48:55	Mutation altering degron motif	0.7503

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*NOTE: the Kaplan plots were collected from OncoLnc