DegronMD - Q9BVH7(ST6GALNAC5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S51L	TCGA-AZ-4315	COAD	TCGA	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0833
p.S51L	DO222391	BTCA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0833
p.S51L	DO8842	COAD	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0833
p.P58L	TCGA-NJ-A4YP	LUAD	TCGA	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.2778
p.P58L	DO218943	LUAD	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.2778
p.P74L	DO233096	GACA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0556
p.G54D	DO233820	GACA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.1667
p.A50S	DO228835	LICA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0556
p.G73D	DO222837	MELA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.0833
p.Q57L	DO229264	THCA	ICGC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.25
p.A72T	SIDM00678	Bladder Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.1111
p.A72T	ACH-000724	Bladder Cancer	CCLE	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.1111
p.Q66K	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.2778
p.Q66K	ACH-000672	Lung Cancer	CCLE	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.2778
p.A52V	SIDM01612	Endometrial Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.1111
p.A52V	ACH-000946	Endometrial/Uterine Cancer	CCLE	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.1111
p.S56P	ACH-002200	Skin Cancer	CCLE	AESST	DEG_SPOP_SBC_1	60:64	Mutation rewiring degron network	0.2222

Kaplan plot for ST6GALNAC5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ST6GALNAC5

UniProt ID: Q9BVH7

Entrez ID: 81849

Protein name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ST6GALNAC5 in