DegronMD - Q9BVL4(SELENOO)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E638K	SIDM01265	Plasma Cell Myeloma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00683	Prostate Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM01090	Colorectal Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00969	Ovarian Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00087	Plasma Cell Myeloma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00654	Small Cell Lung Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00844	Burkitt's Lymphoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00793	Burkitt's Lymphoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM01133	Other Solid Cancers	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00431	T-Lymphoblastic Leukemia	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00720	Mesothelioma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM00808	Burkitt's Lymphoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.E638K	SIDM01254	Burkitt's Lymphoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.1111
p.V665M	SIDM00338	Acute Myeloid Leukemia	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00193	Colorectal Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00573	Glioblastoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00348	Esophageal Squamous Cell Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00013	Melanoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00492	Glioblastoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00612	Glioma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM01577	Plasma Cell Myeloma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM00163	Biliary Tract Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM01446	Glioblastoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM01378	Ovarian Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	SIDM01559	Melanoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	KINGS-1	central nervous system	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	TE-11	oesophagus	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	no-11	central nervous system	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	KYSE-410	oesophagus	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.V665M	AM-38	central nervous system	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.P657L	SIDM00693	Bladder Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.3056
p.P657L	SIDM01732	Non-Cancerous	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.3056
p.A637T	SIDM00890	Melanoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.A637T	C32	skin	COSMIC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.0833
p.G644R	SIDM01608	Endometrial Carcinoma	GDSC	DGRQRSYSSKP	CBL_PTK	646:656	Mutation rewiring degron network	0.2778

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SELENOO

UniProt ID: Q9BVL4

Entrez ID: 83642

Protein name: Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.n1) (Selenoprotein O) (SelO)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SELENOO in