DegronMD - Q9BVT8(TMUB1)

TMUB1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D38N	TCGA-FI-A2D5	UCEC	TCGA	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.1944
p.D38N	DO41331	UCEC	ICGC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.1944
p.P52L	DO222494	MELA	ICGC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.2778
p.A57V	SIDM00615	Hepatocellular Carcinoma	GDSC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.1389
p.A57V	ACH-000217	Liver Cancer	CCLE	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.1389
p.A57V	JHH-6	liver	COSMIC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.1389
p.A54T	SIDM00220	Ovarian Carcinoma	GDSC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.2222
p.A54T	ACH-000962	Ovarian Cancer	CCLE	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.2222
p.A54T	ACH-001145	Ovarian Cancer	CCLE	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.2222
p.A54T	OC-314	ovary	COSMIC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation rewiring degron network	0.2222
p.T48S	SIDM01781	Gastric Carcinoma	GDSC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation altering degron motif	0.6005
p.T48S	ACH-000325	Gastric Cancer	CCLE	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation altering degron motif	0.6005
p.T48A	SIDM00784	Glioma	GDSC	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation altering degron motif	0.6028
p.T48A	ACH-000126	Brain Cancer	CCLE	PSGTPTPS	DEG_SCF_FBW7_1	43:50	Mutation altering degron motif	0.6028

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*NOTE: the Kaplan plots were collected from OncoLnc