SCRT1
UniProt ID: Q9BWW7
Entrez ID: 83482
Protein name: Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (hScrt)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Transcriptional repressor that binds E-box motif CAGGTG. Can modulate the action of basic helix-loop-helix (bHLH) transcription factors, critical for neuronal differentiation. {ECO:0000269|PubMed:11274425}....
FUNCTION: Transcriptional repressor that binds E-box motif CAGGTG. Can modulate the action of basic helix-loop-helix (bHLH) transcription factors, critical for neuronal differentiation. {ECO:0000269|PubMed:11274425}.
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GO - Biological processes (BP):
negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of neuron migration [GO:2001222]; regulation of transcription, DNA-templated [GO:0006355]...
negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of neuron migration [GO:2001222]; regulation of transcription, DNA-templated [GO:0006355]
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GO - Molecular function (MF):
DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region s...
DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]
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GO - Cellular component (CC):
nuclear body [GO:0016604]...
nuclear body [GO:0016604]
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SCRT1
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Kaplan plot for SCRT1 in
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*NOTE: the Kaplan plots were collected from OncoLnc