DegronMD - Q9BXJ9(NAA15)

NAA15

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K665N	TCGA-F5-6814	READ	TCGA	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation blocking ubiquitination signal	0.5278
p.K665N	DO36556	READ	ICGC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation blocking ubiquitination signal	0.5278
p.E651K	TCGA-IR-A3LH	CESC	TCGA	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.591
p.E651K	DO44381	CESC	ICGC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.591
p.E651K	SIDM00333	Endometrial Carcinoma	GDSC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.591
p.E651K	ACH-000988	Endometrial/Uterine Cancer	CCLE	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.591
p.E651K	MFE-319	endometrium	COSMIC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.591
p.E656K	TCGA-IR-A3LH	CESC	TCGA	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.7022
p.E656K	DO44381	CESC	ICGC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation altering degron motif	0.7022
p.P663L	DO42673	UCEC	ICGC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation rewiring degron network	0.1389
p.E640G	SIDM00332	Breast Carcinoma	GDSC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation rewiring degron network	0.0556
p.E640G	ACH-001819	Breast Cancer	CCLE	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation rewiring degron network	0.0556
p.E640G	MFM-223	breast	COSMIC	VETPLEE	DEG_SCF_FBW7_2	650:656	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc