DegronMD - Q9BXK1(KLF16)

KLF16

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R223C	DO230309	COCA	ICGC	ARSTS	DEG_SPOP_SBC_1	222:226	Mutation altering degron motif	0.719
p.T225A	DO228123	EOPC	ICGC	ARSTS	DEG_SPOP_SBC_1	222:226	Mutation altering degron motif	0.7139
p.L216M	DO229027	LICA	ICGC	ARSTS	DEG_SPOP_SBC_1	222:226	Mutation rewiring degron network	0.1667
p.L216M	DO229211	THCA	ICGC	ARSTS	DEG_SPOP_SBC_1	222:226	Mutation rewiring degron network	0.1667
p.P95R	DO218842	SKCA	ICGC	PASSS	DEG_SPOP_SBC_1	100:104	Mutation rewiring degron network	0.1944
p.D229V	DO229218	THCA	ICGC	ARSTS	DEG_SPOP_SBC_1	222:226	Mutation rewiring degron network	0.25
p.S108A	SIDM00777	Colorectal Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	100:104	Mutation blocking phosphorylation signal	0.6667
p.S108A	ACH-000360	Colon/Colorectal Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	100:104	Mutation blocking phosphorylation signal	0.6667
p.A98S	ACH-000314	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	100:104	Mutation rewiring degron network	0.2778
p.S104P	ACH-001554	Eye Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	100:104	Mutation altering degron motif	0.7863

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*NOTE: the Kaplan plots were collected from OncoLnc