DegronMD - Q9BZE3(BARHL1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G127S	TCGA-CV-A468	HNSC	TCGA	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.0556
p.G127S	DO52070	HNSC	ICGC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.0556
p.L313P	DO227802	COCA	ICGC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation rewiring degron network	0.3056
p.V319I	DO38663	STAD	ICGC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.7076
p.P309S	DO229151	THCA	ICGC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation rewiring degron network	0.1944
p.P113L	SIDM01036	Plasma Cell Myeloma	GDSC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7582
p.P113L	ACH-000653	Myeloma	CCLE	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7582
p.P113L	JJN-3	haematopoietic and lymphoid tissue	COSMIC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7582
p.L316M	SIDM00371	Pancreatic Carcinoma	GDSC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.5999
p.L316M	SIDM00552	Rhabdomyosarcoma	GDSC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.5999
p.L316M	ACH-000607	Rhabdoid	CCLE	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.5999
p.L316M	ACH-001421	Eye Cancer	CCLE	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.5999
p.P113H	SIDM00327	Hodgkin's Lymphoma	GDSC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7694
p.P113H	ACH-000754	Lymphoma	CCLE	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7694
p.P113H	L-428	haematopoietic and lymphoid tissue	COSMIC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7694
p.P315T	SIDM00279	Gastric Carcinoma	GDSC	PPLAGVLPR	DEG_SIAH_1	314:322	Mutation altering degron motif	0.7031
p.G118R	GP5d	large intestine	COSMIC	PYSSS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.3056

Kaplan plot for BARHL1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BARHL1

UniProt ID: Q9BZE3

Entrez ID: 56751

Protein name: BarH-like 1 homeobox protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BARHL1 in