DegronMD - Q9BZJ8(GPR61)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S9L	TCGA-60-2698	LUSC	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.0556
p.S9L	DO26469	LUSC	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.0556
p.P23Q	TCGA-80-5608	LUAD	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.7035
p.P23Q	DO23693	LUAD	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.7035
p.P32L	TCGA-97-8172	LUAD	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.P32L	TCGA-AA-3492	COAD	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.P32L	DO8224	COAD	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.P32L	DO26384	LUAD	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.S13T	TCGA-AX-A06F	UCEC	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.S13T	DO41752	UCEC	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.1667
p.G35W	TCGA-BQ-7044	KIRP	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.0833
p.G35W	DO20942	KIRP	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.0833
p.A28S	TCGA-CR-7395	HNSC	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.2778
p.A28S	DO14274	HNSC	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.2778
p.P25L	TCGA-D9-A149	SKCM	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.6471
p.P25L	DO37420	SKCM	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.6471
p.P20H	TCGA-DJ-A2QB	THCA	TCGA	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.6583
p.P20H	DO39421	THCA	ICGC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.6583
p.R18S	SIDM01770	Gastric Carcinoma	GDSC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation rewiring degron network	0.3056
p.Q21H	ACH-002192	Kidney Cancer	CCLE	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.647
p.Q21H	RCC-MF	kidney	COSMIC	VPQTPGPS	DEG_SCF_FBW7_1	19:26	Mutation altering degron motif	0.647

Kaplan plot for GPR61 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GPR61

UniProt ID: Q9BZJ8

Entrez ID: 83873

Protein name: G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GPR61 in