DegronMD - Q9BZM2(PLA2G2F)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.C154Y	TCGA-22-5478	LUSC	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1111
p.C154Y	DO27011	LUSC	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1111
p.C156Y	TCGA-AX-A2HA	UCEC	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.0556
p.C156Y	DO42504	UCEC	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.0556
p.E134K	TCGA-EB-A431	SKCM	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1389
p.E134K	DO37671	SKCM	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1389
p.E138D	TCGA-EY-A1GS	UCEC	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.25
p.E138D	DO43162	UCEC	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.25
p.H131D	TCGA-JW-A5VL	CESC	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.0556
p.H131D	DO49976	CESC	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.0556
p.T147S	TCGA-VQ-A8PT	STAD	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.3056
p.T147S	DO51776	STAD	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.3056
p.E138K	TCGA-WE-A8K6	SKCM	TCGA	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.25
p.E138K	DO51283	SKCM	ICGC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.25
p.I133F	SIDM01175	Other Sarcomas	GDSC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1111
p.I133F	ACH-002309	Sarcoma	CCLE	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1111
p.I133F	SW684	soft tissue	COSMIC	PTPNCS	DEG_SCF_FBW7_1	141:146	Mutation rewiring degron network	0.1111

Kaplan plot for PLA2G2F in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

PLA2G2F

UniProt ID: Q9BZM2

Entrez ID: 64600

Protein name: Group IIF secretory phospholipase A2 (GIIF sPLA2) (sPLA2-IIF) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 2F)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for PLA2G2F in