DegronMD - Q9BZM6(ULBP1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S212C	TCGA-21-5782	LUSC	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556
p.S212C	DO27120	LUSC	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556
p.D206Y	TCGA-73-A9RS	LUAD	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2222
p.D206Y	DO51193	LUAD	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2222
p.F197V	TCGA-76-6662	GBM	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation altering degron motif	0.5957
p.F197V	DO11681	GBM	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation altering degron motif	0.5957
p.F197L	TCGA-AJ-A3EL	UCEC	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation altering degron motif	0.587
p.F197L	DO41542	UCEC	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation altering degron motif	0.587
p.K191N	TCGA-AX-A2HH	UCEC	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation substituting flanking lysine	0.2778
p.K191N	DO43057	UCEC	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation substituting flanking lysine	0.2778
p.W193R	TCGA-CR-7370	HNSC	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2222
p.W193R	DO14426	HNSC	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2222
p.P211L	TCGA-EE-A29C	SKCM	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0833
p.P211L	DO222727	MELA	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0833
p.P211L	DO38028	SKCM	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0833
p.M204L	TCGA-EE-A3AB	SKCM	TCGA	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2778
p.M204L	DO222670	MELA	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2778
p.M204L	DO38057	SKCM	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.2778
p.D189G	DO222877	COCA	ICGC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.1111
p.L187M	SIDM01180	Hepatocellular Carcinoma	GDSC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556
p.L187M	ACH-000478	Liver Cancer	CCLE	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556
p.L187M	SNU-387	liver	COSMIC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556
p.M199I	SIDM00929	Chondrosarcoma	GDSC	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation altering degron motif	0.6507
p.S212Y	ACH-002256	Leukemia	CCLE	FLMYWE	LIG_APCC_ABBA_1	197:202	Mutation rewiring degron network	0.0556

Kaplan plot for ULBP1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ULBP1

UniProt ID: Q9BZM6

Entrez ID: 80329

Protein name: UL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ULBP1 in