DegronMD - Q9BZQ4(NMNAT2)

NMNAT2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S115Y	TCGA-22-5472	LUSC	TCGA	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.2778
p.S115Y	DO27421	LUSC	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.2778
p.G127R	TCGA-D9-A6E9	SKCM	TCGA	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.2222
p.G127R	DO50289	SKCM	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.2222
p.E132K	DO224721	COCA	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.0833
p.P129A	DO228091	EOPC	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.1667
p.S121Y	DO231031	LUSC	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation altering degron motif	0.6009
p.S115F	DO229459	SKCA	ICGC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation rewiring degron network	0.2778
p.T123K	ACH-002089	Lung Cancer	CCLE	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation altering degron motif	0.7306
p.T123K	201T	lung	COSMIC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation altering degron motif	0.7306
p.T118K	201T	lung	COSMIC	VNTPSMT	DEG_SCF_FBW7_1	117:123	Mutation altering degron motif	0.7306

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*NOTE: the Kaplan plots were collected from OncoLnc