DegronMD - Q9BZV3(IMPG2)

IMPG2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E680D	SIDM02059	Colorectal Carcinoma	GDSC	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation rewiring degron network	0.1389
p.A691P	SIDM00769	Non-Small Cell Lung Carcinoma	GDSC	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6392
p.A691P	ACH-000733	Lung Cancer	CCLE	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6392
p.A691P	NCI-H1838	lung	COSMIC	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6392
p.D692N	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6932
p.D692N	ACH-000694	Esophageal Cancer	CCLE	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6932
p.D692N	TE-9	oesophagus	COSMIC	VPIFAD	LIG_APCC_ABBA_1	687:692	Mutation altering degron motif	0.6932

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*NOTE: the Kaplan plots were collected from OncoLnc