DegronMD - Q9C0J8(WDR33)

WDR33

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M411V	TCGA-BR-4362	STAD	TCGA	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.2778
p.M411V	DO38336	STAD	ICGC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.2778
p.R406Q	TCGA-CG-4460	STAD	TCGA	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.1389
p.R406Q	DO38427	STAD	ICGC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.1389
p.R404Q	TCGA-EE-A2MS	SKCM	TCGA	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.0833
p.R404Q	DO37567	SKCM	ICGC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.0833
p.G427R	TCGA-HD-7832	HNSC	TCGA	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.1667
p.G427R	DO16061	HNSC	ICGC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.1667
p.D431G	DO228636	PRAD	ICGC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation rewiring degron network	0.0556
p.R414Q	SIDM00238	Ovarian Carcinoma	GDSC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation altering degron motif	0.7329
p.R414Q	ACH-000947	Ovarian Cancer	CCLE	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation altering degron motif	0.7329
p.R414Q	OVK-18	ovary	COSMIC	DRYNLNLLP	DEG_APCC_DBOX_1	413:421	Mutation altering degron motif	0.7329

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*NOTE: the Kaplan plots were collected from OncoLnc