DegronMD - Q9C0K7(STRADB)

STRADB

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L383R	TCGA-B5-A5OC	UCEC	TCGA	PPAY	ITCH	385:388	Mutation rewiring degron network	0.2778
p.L383R	DO52405	UCEC	ICGC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.2778
p.N389S	TCGA-CG-5721	STAD	TCGA	PPAY	ITCH	385:388	Mutation rewiring degron network	0.3056
p.N389S	DO38192	STAD	ICGC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.3056
p.N389S	SIDM01779	Gastric Carcinoma	GDSC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.3056
p.N389S	ACH-000761	Gastric Cancer	CCLE	PPAY	ITCH	385:388	Mutation rewiring degron network	0.3056
p.D309H	TCGA-D6-A4ZB	HNSC	TCGA	DSGIGES	DEG_SCF_TRCP1_1	309:315	Mutation altering degron motif	0.7688
p.D309H	DO44446	HNSC	ICGC	DSGIGES	DEG_SCF_TRCP1_1	309:315	Mutation altering degron motif	0.7688
p.E375Q	TCGA-JW-A5VL	CESC	TCGA	PPAY	ITCH	385:388	Mutation rewiring degron network	0.0556
p.E375Q	DO49976	CESC	ICGC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.0556
p.I393M	DO45305	LIRI	ICGC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.1944
p.F376S	SIDM00068	Colorectal Carcinoma	GDSC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.0833
p.F376S	GEO	large intestine	COSMIC	PPAY	ITCH	385:388	Mutation rewiring degron network	0.0833
p.G307D	SIDM01608	Endometrial Carcinoma	GDSC	DSGIGES	DEG_SCF_TRCP1_1	309:315	Mutation rewiring degron network	0.2778
p.G307D	ACH-000990	Endometrial/Uterine Cancer	CCLE	DSGIGES	DEG_SCF_TRCP1_1	309:315	Mutation rewiring degron network	0.2778
p.S299C	ACH-000831	Endometrial/Uterine Cancer	CCLE	DSGIGES	DEG_SCF_TRCP1_1	309:315	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc