DegronMD - Q9GZN6(SLC6A16)

SLC6A16

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L721I	TCGA-B5-A11N	UCEC	TCGA	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.1389
p.L721I	TCGA-EO-A22X	UCEC	TCGA	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.1389
p.L721I	DO43907	UCEC	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.1389
p.L721I	DO41458	UCEC	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.1389
p.E718K	TCGA-EE-A2MT	SKCM	TCGA	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.2222
p.E718K	DO38051	SKCM	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.2222
p.P711S	TCGA-XK-AAIW	PRAD	TCGA	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation altering degron motif	0.6752
p.P711S	DO51407	PRAD	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation altering degron motif	0.6752
p.V715L	DO232031	LICA	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.3056
p.A699D	DO229036	LICA	ICGC	LTPSKE	DEG_SCF_FBW7_2	709:714	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc