DegronMD - Q9GZQ6(NPFFR1)

NPFFR1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D380N	DO225046	BRCA	ICGC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation altering degron motif	0.6932
p.R371W	DO229389	BTCA	ICGC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.0833
p.R371W	DO234401	ESAD	ICGC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.0833
p.S391R	DO50346	ESAD	ICGC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.1667
p.R377Q	DO228322	MALY	ICGC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.25
p.R377Q	SIDM00867	Glioblastoma	GDSC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.25
p.R377Q	ACH-001636	Lymphoma	CCLE	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.25
p.R377W	SIDM00582	Pancreatic Carcinoma	GDSC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.25
p.R377W	SIDM00589	Oral Cavity Carcinoma	GDSC	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.25
p.S379N	ACH-000975	Lung Cancer	CCLE	DSGLPS	DEG_SCF_TRCP1_1	380:385	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc