DegronMD - Q9GZS3(WDR61)

WDR61

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W24C	TCGA-95-7043	LUAD	TCGA	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.2222
p.W24C	DO24739	LUAD	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.2222
p.T26I	TCGA-D1-A2G0	UCEC	TCGA	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.2778
p.T26I	DO43049	UCEC	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.2778
p.F40S	DO222410	BTCA	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.1111
p.A29T	DO8240	COAD	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation altering degron motif	0.7139
p.T26K	DO229019	LICA	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.2778
p.H33N	DO229022	LICA	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.3056
p.T30A	DO48759	LIRI	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation altering degron motif	0.7139
p.G31E	DO26999	LUSC	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation altering degron motif	0.7199
p.N27S	DO229065	PRAD	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.3056
p.A20T	DO229218	THCA	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.1111
p.N38D	DO42033	UCEC	ICGC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.1667
p.E33Q	SIDM00866	Breast Carcinoma	GDSC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.3056
p.E33Q	SIDM00868	Non-Cancerous	GDSC	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.3056
p.E33Q	ACH-000374	Breast Cancer	CCLE	KKENS	DEG_APCC_KENBOX_2	28:32	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc