DegronMD - Q9H0A6(RNF32)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K50T	TCGA-A5-A0G2	UCEC	TCGA	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation altering degron motif	0.6195
p.K50T	DO41235	UCEC	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation altering degron motif	0.6195
p.S51Y	TCGA-AJ-A5DW	UCEC	TCGA	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.3056
p.S51Y	DO229213	THCA	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.3056
p.S51Y	DO50075	UCEC	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.3056
p.I60M	TCGA-CG-5721	STAD	TCGA	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.0556
p.I60M	DO38192	STAD	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.0556
p.Q45K	TCGA-EO-A3B0	UCEC	TCGA	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.3056
p.Q45K	DO219773	UCEC	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.3056
p.A58V	DO228935	COCA	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.1111
p.L52Q	DO232852	NACA	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.2778
p.L52I	DO232852	NACA	ICGC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.2778
p.Q43P	SIDM01727	Chronic Myelogenous Leukemia	GDSC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.25
p.Q43P	ACH-000241	Leukemia	CCLE	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.25
p.D55N	SIDM01588	Endometrial Carcinoma	GDSC	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.1944
p.D55N	ACH-000993	Endometrial/Uterine Cancer	CCLE	KKENK	DEG_APCC_KENBOX_2	46:50	Mutation rewiring degron network	0.1944

Kaplan plot for RNF32 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RNF32

UniProt ID: Q9H0A6

Entrez ID: 140545

Protein name: RING finger protein 32

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RNF32 in