DegronMD - Q9H0U6(MRPL18)

MRPL18

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A32V	TCGA-A6-5661	COAD	TCGA	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.1944
p.A32V	DO8634	COAD	ICGC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.1944
p.A32V	DO229018	LICA	ICGC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.1944
p.D37G	TCGA-FI-A2D5	UCEC	TCGA	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.0556
p.D37G	DO41331	UCEC	ICGC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.0556
p.S27N	DO52661	MALY	ICGC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation altering degron motif	0.7069
p.S27R	DO232224	PBCA	ICGC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation altering degron motif	0.7427
p.F21L	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.2778
p.F21L	ACH-000914	Lymphoma	CCLE	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.2778
p.F21L	HT	haematopoietic and lymphoid tissue	COSMIC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.2778
p.D37H	SIDM01186	Breast Carcinoma	GDSC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.0556
p.D37H	ACH-000554	Breast Cancer	CCLE	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.0556
p.D37H	UACC-893	breast	COSMIC	ALSTS	DEG_SPOP_SBC_1	23:27	Mutation rewiring degron network	0.0556

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc