DegronMD - Q9H0V9(LMAN2L)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G121A	TCGA-3A-A9IU	PAAD	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.3056
p.K136M	TCGA-86-8279	LUAD	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation substituting flanking lysine	0.2222
p.Y134C	TCGA-94-7557	LUSC	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.1667
p.R138L	TCGA-BF-A1PZ	SKCM	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.0556
p.K123N	TCGA-BS-A0TC	UCEC	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation altering degron motif	0.5806
p.F115L	TCGA-EY-A1G8	UCEC	TCGA	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.1389
p.F115L	DO43578	UCEC	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.1389
p.L131F	DO44038	BLCA	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.25
p.I117V	DO233831	GACA	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.1944
p.H118N	DO229045	LICA	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.2222
p.D131N	DO24940	LUAD	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.25
p.D127A	DO42673	UCEC	ICGC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation altering degron motif	0.7793
p.G129S	SIDM00113	Kidney Carcinoma	GDSC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.3056
p.G129S	ACH-001208	Kidney Cancer	CCLE	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.3056
p.G129S	TK10	kidney	COSMIC	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.3056
p.V113G	ACH-000463	Lung Cancer	CCLE	KKNLHGD	LIG_APCC_ABBAyCdc20_2	122:128	Mutation rewiring degron network	0.0833

Kaplan plot for LMAN2L in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

LMAN2L

UniProt ID: Q9H0V9

Entrez ID: 81562

Protein name: VIP36-like protein (Lectin mannose-binding 2-like) (LMAN2-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for LMAN2L in