DegronMD - Q9H161(ALX4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G85D	TCGA-AJ-A3EL	UCEC	TCGA	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.1667
p.G85D	DO41542	UCEC	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.1667
p.R63Q	TCGA-AY-6197	COAD	TCGA	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.0556
p.R63Q	DO9956	COAD	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.0556
p.G69E	TCGA-CI-6624	READ	TCGA	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.2222
p.G69E	DO37130	READ	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.2222
p.R63W	DO233109	GACA	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.0556
p.R84W	DO233636	GACA	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.1944
p.P76T	DO229353	LAML	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation altering degron motif	0.7031
p.P76T	SIDM00233	T-Lymphoblastic Leukemia	GDSC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation altering degron motif	0.7031
p.A68D	DO38404	STAD	ICGC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.1944
p.D72E	SIDM00760	Small Cell Lung Carcinoma	GDSC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.3056
p.D72E	ACH-000729	Lung Cancer	CCLE	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.3056
p.G85S	SIDM01590	Breast Carcinoma	GDSC	LATPLES	DEG_SCF_FBW7_1	73:79	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons