DegronMD - Q9H169(STMN4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E160K	TCGA-EB-A431	SKCM	TCGA	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.2222
p.N161D	TCGA-EY-A1GQ	UCEC	TCGA	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1944
p.N161D	DO43090	UCEC	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1944
p.E154K	DO223588	BLCA	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation altering degron motif	0.7022
p.R166W	DO234429	ESAD	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.0556
p.R166W	DO233623	GACA	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.0556
p.R166W	DO47981	STAD	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.0556
p.A161D	DO233154	GACA	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1944
p.A161D	DO38483	STAD	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1944
p.E150K	DO13845	GBM	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.2778
p.E150K	DO222837	MELA	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.2778
p.A158T	DO228665	PRAD	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.2778
p.A161T	DO43306	UCEC	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1944
p.E154D	DO43154	UCEC	ICGC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation altering degron motif	0.6758
p.R151K	SIDM00351	Oral Cavity Carcinoma	GDSC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.3056
p.R151K	SAS	upper aerodigestive tract	COSMIC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.3056
p.E143K	ACH-000835	Sarcoma	CCLE	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.0833
p.E143K	GCT	soft tissue	COSMIC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.0833
p.A146T	ACH-000978	Endometrial/Uterine Cancer	CCLE	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1667
p.A146T	EN	endometrium	COSMIC	NKENR	DEG_APCC_KENBOX_2	152:156	Mutation rewiring degron network	0.1667

Kaplan plot for STMN4 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

STMN4

UniProt ID: Q9H169

Entrez ID: 81551

Protein name: Stathmin-4 (Stathmin-like protein B3) (RB3)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for STMN4 in