DegronMD - Q9H1E3(NUCKS1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P33A	TCGA-17-Z045	LUAD	TCGA	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.6392
p.P33L	TCGA-AP-A0LG	UCEC	TCGA	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.6471
p.P33L	DO41823	UCEC	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.6471
p.S30L	TCGA-CA-6717	COAD	TCGA	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.8778
p.S30L	DO8264	COAD	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.8778
p.S30L	DO222762	COCA	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.8778
p.G31S	TCGA-FI-A2F4	UCEC	TCGA	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.6993
p.G31S	DO43434	UCEC	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.6993
p.R42Q	DO222524	ESCA	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation rewiring degron network	0.1111
p.R42Q	SIDM01619	Endometrial Carcinoma	GDSC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation rewiring degron network	0.1111
p.R42Q	ACH-000984	Endometrial/Uterine Cancer	CCLE	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation rewiring degron network	0.1111
p.P32T	DO229032	LICA	ICGC	DSGPPT	DEG_SCF_TRCP1_1	29:34	Mutation altering degron motif	0.5919

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons