DegronMD - Q9H1I8(ASCC2)

ASCC2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P527S	TCGA-PK-A5HB	ACC	TCGA	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation altering degron motif	0.6752
p.E524D	DO6428	CLLE	ICGC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.25
p.P529S	SIDM00935	Other Solid Cancers	GDSC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation altering degron motif	0.5641
p.P529S	SIDM00678	Bladder Carcinoma	GDSC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation altering degron motif	0.5641
p.N542D	SIDM00810	Non-Small Cell Lung Carcinoma	GDSC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1111
p.N542D	ACH-000757	Lung Cancer	CCLE	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1111
p.N542D	A427	lung	COSMIC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1111
p.R519C	SIDM00364	B-Lymphoblastic Leukemia	GDSC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1111
p.R519C	P30-OHK	haematopoietic and lymphoid tissue	COSMIC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1111
p.L521R	ACH-000975	Lung Cancer	CCLE	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation rewiring degron network	0.1667
p.S528C	NCI-H1770	lung	COSMIC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation altering degron motif	0.7541
p.P530S	WSU-NHL	haematopoietic and lymphoid tissue	COSMIC	PDPTPLLT	DEG_SCF_FBW7_1	527:534	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc