DegronMD - Q9H1Z4(WDR13)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y78F	TCGA-44-2657	LUAD	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.1111
p.Y78F	DO25020	LUAD	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.1111
p.V83I	TCGA-AA-3854	COAD	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.25
p.V83I	DO10148	COAD	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.25
p.A77S	TCGA-CK-4951	COAD	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.0833
p.A77S	DO10582	COAD	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.0833
p.D99N	TCGA-D3-A8GV	SKCM	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.1944
p.D99N	DO219477	SKCM	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.1944
p.L90F	TCGA-DK-A3IS	BLCA	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.6981
p.L90F	DO566	BLCA	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.6981
p.L90F	ACH-001377	Pancreatic Cancer	CCLE	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.6981
p.R92S	TCGA-EE-A3AC	SKCM	TCGA	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.6316
p.R92S	DO37631	SKCM	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.6316
p.R92H	DO233941	GACA	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.7133
p.R84S	DO229044	LICA	ICGC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation rewiring degron network	0.2778
p.R87H	SIDM00839	Colorectal Carcinoma	GDSC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.8244
p.R87H	ACH-000950	Colon/Colorectal Cancer	CCLE	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.8244
p.R87H	LoVo	large intestine	COSMIC	SRTTLDRME	DEG_APCC_DBOX_1	86:94	Mutation altering degron motif	0.8244

Kaplan plot for WDR13 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

WDR13

UniProt ID: Q9H1Z4

Entrez ID: 64743

Protein name: WD repeat-containing protein 13

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for WDR13 in