FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a reg...
FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. {ECO:0000250}.
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GO - Biological processes (BP):
adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; regulation of metabolic process [GO:0019222]; regulation of neuron differentiation [GO:0045664]...
adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; regulation of metabolic process [GO:0019222]; regulation of neuron differentiation [GO:0045664]
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GO - Molecular function (MF):
G protein-coupled receptor activity [GO:0004930]; sphingosine-1-phosphate receptor activity [GO:0038036]...
G protein-coupled receptor activity [GO:0004930]; sphingosine-1-phosphate receptor activity [GO:0038036]
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GO - Cellular component (CC):
cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]...
cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]
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