DegronMD - Q9H2A2(ALDH8A1)

ALDH8A1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S22I	TCGA-17-Z052	LUAD	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1389
p.T32A	TCGA-92-7341	LUSC	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.7139
p.T32A	DO26677	LUSC	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.7139
p.N41T	TCGA-A5-A0G1	UCEC	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1389
p.N41T	DO42472	UCEC	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1389
p.C21R	TCGA-BR-6452	STAD	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1111
p.C21R	DO38404	STAD	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1111
p.D29N	TCGA-ND-A4WC	UCS	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.5821
p.S23L	TCGA-Z2-A8RT	SKCM	TCGA	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1667
p.S23L	DO51301	SKCM	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1667
p.P40L	DO228483	BRCA	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.1667
p.S27F	DO233621	GACA	ICGC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation rewiring degron network	0.2778
p.G33W	SIDM01183	Other Solid Cancers	GDSC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.7825
p.G33W	ACH-001417	Lung Cancer	CCLE	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.7825
p.G33W	UMC-11	lung	COSMIC	DPSTGE	DEG_Kelch_Keap1_1	29:34	Mutation altering degron motif	0.7825

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*NOTE: the Kaplan plots were collected from OncoLnc