DegronMD - Q9H3C7(GGNBP2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E404D	TCGA-19-5956	GBM	TCGA	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.E404D	DO13863	GBM	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.N383S	TCGA-AP-A051	UCEC	TCGA	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.1667
p.N383S	DO42673	UCEC	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.1667
p.R381Q	TCGA-F5-6814	READ	TCGA	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.1111
p.R381Q	DO36556	READ	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.1111
p.E404K	TCGA-GV-A3JZ	BLCA	TCGA	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.E404K	DO773	BLCA	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.R380K	TCGA-NC-A5HL	LUSC	TCGA	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.R380K	DO219193	LUSC	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.0833
p.V386M	DO228935	COCA	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.25
p.I389F	DO231902	LINC	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation altering degron motif	0.7415
p.P392S	DO220907	MELA	ICGC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation altering degron motif	0.6752
p.E398K	SIDM00150	Colorectal Carcinoma	GDSC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.25
p.E398K	ACH-000969	Colon/Colorectal Cancer	CCLE	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.25
p.C385Y	SIDM01608	Endometrial Carcinoma	GDSC	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.2222
p.C385Y	ACH-000990	Endometrial/Uterine Cancer	CCLE	IPTPLQT	DEG_SCF_FBW7_1	389:395	Mutation rewiring degron network	0.2222

Kaplan plot for GGNBP2 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GGNBP2

UniProt ID: Q9H3C7

Entrez ID: 79893

Protein name: Gametogenetin-binding protein 2 (Laryngeal carcinoma-related protein 1) (Protein ZNF403)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for GGNBP2 in