DegronMD - Q9H3T2(SEMA6C)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R688Q	TCGA-DD-AADK	LIHC	TCGA	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.0556
p.R713L	DO12586	GBM	ICGC	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.0833
p.P708S	DO229211	THCA	ICGC	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.2222
p.P696L	SIDM01721	Non-Cancerous	GDSC	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.2778
p.H711R	ACH-000937	Leukemia	CCLE	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.1389
p.A696V	ACH-000983	Leukemia	CCLE	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.2778
p.R713H	ACH-000984	Endometrial/Uterine Cancer	CCLE	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.0833
p.P692L	ACH-001605	Brain Cancer	CCLE	LPTPEST	DEG_SCF_FBW7_1	698:704	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons